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| Australian Open | ||
| Surface: Hard | Date: Jan. 14 - Jan. 27 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | James Duckworth | Win | 6-4, 6-3, 7-5 |
| Second Round | Matthew Ebden | Win | 6-3, 6-2, 6-2 |
| Third Round | Alex De Minaur | Win | 6-1, 6-2, 6-4 |
| Fourth Round | Tomas Berdych | Win | 6-0, 6-1, 7-6 (7-4) |
| Quarterfinals | Frances Tiafoe | Win | 6-3, 6-4, 6-2 |
| Semifinals | Stefanos Tsitsipas | Win | 6-2, 6-4, 6-0 |
| Final | Novak Djokovic | Loss | 3-6, 2-6, 3-6 |
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